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Tuesday, May 7, 2013

Is Mariah/Nicki Feud Real? Yes, And Also Great Publicity

Most celebrity feuds unfold remotely. When Angelina Jolie bragged to Vogue about snagging the then-married Brad Pitt, Jennifer Aniston's retort -- "What Angelina did was very uncool" -- appeared only several months later (in the same magazine). Other celebrities, like LeAnn Rimes and Brandi Glanville, have waged war in real time, but from the comfort of whatever green room or limo they happen to be occupying. Twitter delivers their barbs for them.

Source: http://www.ivillage.com/mariah-careynicki-minaj-american-idol-feud-real-its-also-great-publicity/1-a-535385?dst=iv%3AiVillage%3Amariah-careynicki-minaj-american-idol-feud-real-its-also-great-publicity-535385

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Monday, May 6, 2013

More hurricanes for Hawaii?

May 5, 2013 ? News of a hurricane threat sends our hearts racing, glues us to the Internet for updates, and makes us rush to the store to stock up on staples. Hawaii, fortunately, has been largely free from these violent storms in the recent past, only two having made landfall in more than 30 years.

Now a study headed by a team of scientists at the International Pacific Research Center, University of Hawaii at Manoa, shows that Hawaii could see a two-to-three-fold increase in tropical cyclones by the last quarter of this century. The study, which appears in the May 5, 2013, online issue of Nature Climate Change, though, leaves open the question, how worried Island residents should get.

"Computer models run with global warming scenarios generally project a decrease in tropical cyclones worldwide. This, though, may not be what will happen with local communities," says lead author Hiroyuki Murakami.

To determine whether tropical cyclones will become more frequent in Hawaii with climate change, Murakami and climate expert Bin Wang at the Meteorology Department, University of Hawaii at Manoa, joined forces with Akio Kitoh at the Meteorological Research Institute and the University of Tsukuba in Japan. The scientists compared in a state-of-the-art, high-resolution global climate model the recent history of tropical cyclones in the North Pacific with a future (2075-2099) scenario, under which greenhouse gas emissions continue to rise, resulting in temperatures about 2?C higher than today.

"In our study, we looked at all tropical cyclones, which range in intensity from tropical storms to full-blown category 5 hurricanes. From 1979 to 2003, both observational records and our model document that only every four years on average did a tropical cyclone come near Hawaii. Our projections for the end of this century show a two-to-three-fold increase for this region," explains Murakami.

The main factors responsible for the increase are changes in the large-scale moisture conditions, the flow patterns in the wind, and in surface temperature patterns stemming from global warming.

Most hurricanes that might threaten Hawaii now are born in the eastern Pacific, south of the Baja California Peninsula. From June through November the ingredients there are just right for tropical cyclone formation, with warm ocean temperatures, lots of moisture, and weak vertical wind shear. But during the storms' long journey across the 3000 miles to Hawaii, they usually fizzle out due to dry conditions over the subtropical central Pacific and the wind shear from the westerly subtropical jet.

Surprisingly, even though fewer tropical cyclones will form in the eastern Pacific in Murakami's future scenario, we can expect more of them to make their way to Hawaii.

The upper-level westerly subtropical jet will move poleward so that the mean steering flow becomes easterly. Thus, storms from Baja California are much more likely to make it to Hawaii. Furthermore, since the climate models also project that the equatorial central Pacific will heat up, conditions may become more favorable for hurricane formation in the open ocean to the south or southeast of Hawaii.

"Our finding that more tropical cyclones will approach Hawaii as Earth continues to warm is fairly robust because we ran our experiments with different model versions and under varying conditions. The yearly number we project, however, still remains very low," reassures study co-author Wang.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/x-cborZ3cwc/130505145937.htm

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Motherless Daughters: Coping With Your Loss | World of Psychology

Motherless Daughters: Coping With Your Loss Research tends to overlook young adults who lose their moms, according to Taranjit (Tara) K. Bhatia, PsyD, a clinical psychologist who specializes in relationships, including mother-daughter bonds. Because they?re already adults, people assume these daughters don?t need maternal guidance.

However, losing a mom has a powerful effect on young adult daughters. In her research, Bhatia found that a daughter?s sense of identity is especially shaken. ?They don?t know what being a woman is all about.?

Daughters also doubt their own role as mothers. ?Most motherless daughters are very insecure about how well they could mother without their mothers? advice, support and reassurance.?

Cultural identity is affected, as well. As kids and teens, many daughters are too busy with school and other activities to focus on their traditions, Bhatia said. They assume they?ll be able to learn from their moms in the future. But once their mothers pass away, they ?find they don?t have anyone to learn from.?

Many daughters feel like orphans, Bhatia said. Fathers may become ?absent and withdrawn, and are unable to tend to their [children?s] emotional needs.? Moms typically form the foundation of the family. They ?take care of everyone and keep the family together. If there is a conflict, mom is the mediator.? So when mothers pass away, the family can fall apart. To regain their family?s stability, daughters set aside their own grief and assume their mother?s role.

Motherless daughters also can experience a persistent grief for years, which peaks during milestones, like their own pregnancy and post-delivery. ?When you become a mother yourself you want to be mothered,? Bhatia said.

Daughters who didn?t have good relationships with their moms still experience a profound grief. They grieve for what could?ve been. ?They grieve for the opportunity to improve their relationship,? Bhatia said.

Motherless daughters may have problems with their other relationships. They tend to feel especially distant from their peers, because of both ?jealousy and lack of commonality.?

?In intimate relationships, motherless daughters are far more needy because they?re trying to fill that void. They try to find in their intimate partners that nurturing that they used to get from their moms.? They?re also not able to give much back to their partners, which causes resentment.

To prevent this, Bhatia suggested motherless daughters gain insight into their behaviors and ?utilize other resources to gain that nurturing, such as a friend or maternal figure.? Individual and couples counseling also can help.

Below, Bhatia shared other suggestions for motherless daughters to cope healthfully with their loss.

1. Carry on your mom?s traditions.

Instead of solely focusing on your loss, incorporate the traditions you grew up with into your own life, Bhatia said. If you?re a mother, this also is a great way to teach your kids about their grandmother, she said.

2. Participate in fundraising efforts.

Helping others who are in a similar situation can be a tribute to your mom, Bhatia said. For instance, if your mom passed away from cancer, you might participate in events sponsored by the American Cancer Society, or make a yearly financial contribution.

3. Create a collage.

A collage is a tangible tool for retaining your connection with your mom, according to Bhatia. It?s a way for you to see her every day and feel her presence, she said. ?Instead of forcing yourself to disconnect and get over your loss, what?s more helpful is to hold onto your memories and keep those connections.?

4. Accept your different identity.

Again, a mother?s passing is a powerful loss, which can change your identity. Bhatia wants readers to know that this is OK. It?s OK if you?re different today. ?Allow yourself the opportunity to explore different prospects without the approval of your mom.? If your mom wasn?t supportive of your career or life choices in the past, ?understand that as time progresses, things change. [Your] mom?s opinions would?ve evolved, as well.? For many daughters, their image of mom stays static, she said, but people naturally change over time.

5. Participate in support groups.

Many motherless daughters feel like they don?t fit in and can?t relate to their peers, Bhatia said. Talking with women who?ve also lost their moms and share similar experiences reminds you that you?re not alone. It helps you connect with others, create a sense of belonging and build a support system.

6. Find a maternal figure.

For instance, you might become close with one of your mom?s friends, who are often very similar to your mom, Bhatia said. And you might learn more about your mom, she said. ?When you?re not able to do that, seek out older females who might help to guide you ? almost like a maternal surrogate.?

7. Seek individual or family therapy.

For the participants in Bhatia?s study, individual therapy was incredibly helpful in processing their mother?s passing. Family therapy also is helpful for daughters, dads and siblings to process their grief and be honest with each other in a supportive environment, Bhatia said.

Coping on Mother?s Day

Naturally, Mother?s Day can be especially hard for motherless daughters. ?Many motherless moms don?t celebrate the day and deprive themselves of that opportunity,? Bhatia said. They may feel guilty for celebrating without their mothers.

Bhatia encouraged daughters to celebrate the day and enjoy the appreciation of their families. This ?reflects the fruits of their own mothers? labor and thus honors them, for they wouldn?t be the mothers they are without that strong primary attachment.?

Also, motherless daughters can continue to buy a card for their moms, she said. In it, they can express what they truly want to say to their moms and reconnect in a meaningful way.

As Bhatia said, ?just because your mom is gone, it doesn?t mean you?ve lost your attachment or connection to her. Your mom will always be there to help you navigate through life.?

Margarita Tartakovsky, M.S. is an Associate Editor at Psych Central and blogs regularly about eating and self-image issues on her own blog, Weightless.

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Catch up on other posts by Margarita Tartakovsky, M.S. (or subscribe to their feed).

????Last reviewed: By John M. Grohol, Psy.D. on 2 May 2013
????Published on PsychCentral.com. All rights reserved.

APA Reference
Tartakovsky, M. (2013). Motherless Daughters: Coping With Your Loss. Psych Central. Retrieved on May 5, 2013, from http://psychcentral.com/blog/archives/2013/05/04/motherless-daughters-coping-with-your-loss/

Source: http://psychcentral.com/blog/archives/2013/05/04/motherless-daughters-coping-with-your-loss/

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Sunday, May 5, 2013

Marco Rubio: The Immigration Reform Opportunity (WSJ)

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Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/303285455?client_source=feed&format=rss

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Scientists create genetically altered mice to model human disease

Friday, May 3, 2013

Whitehead Institute Founding Member Rudolf Jaenisch, who helped transform the study of genetics by creating the first transgenic mouse in 1974, is again revolutionizing how genetically altered animal models are created and perhaps even redefining what species may serve as models.

"This new method is a game changer," says Jaenisch, who is also a professor of biology at MIT. "We can now make a mouse with five mutations in just three to four weeks, whereas the conventional way would take three to four years. And it's rather straightforward, probably even easier than the conventional way."

Scientists create models in mice by altering specific genes that have been associated with a given disease. The models allow for the study of the development and course of the disease and the effects of various interventions, including genetic and chemical. For the past 20 years, the creation of such models has remained relatively unchanged: scientists insert a piece of DNA into a mouse embryonic stem (ES) cell, inject the modified cell into a very early-stage embryo, called a blastocyst, then implant this developing ball of cells into a foster female mouse. The whole process can take years and tens of thousands of dollars to establish a mouse strain with, for example, a single copy of a gene "knocked out". Such knockouts can only be created in very few species, including mice and rats, whose ES cells can be grown and modified reliably.

The new approach used by scientists in Jaenisch's lab bypasses ES cells to quickly and efficiently produce mice with mutations in both copies of multiple genes. In next week's issue of the journal Cell, Haoyi Wang, Hui Yang, and Chikdu Shivalila describe their technique, which is based on a system that certain bacteria use to fend off viral attacks.

This is the first time that the system, known as CRISPR (for "clustered regularly interspaced short palindromic repeat")/Cas (for "CRISPR-associated"), has been used to alter multiple genes in a single multicellular organism. Shivalila says the process is so accessible that he expects other labs to adopt it quickly.

"For any institution or university with a core facility, we think this will be the way they will start making mice carrying specific mutations because it's a lot faster and so efficient," says Shivalila, one of Jaenisch's graduate students. "We were surprised that we could get two genes 'knocked out' at four loci very, very efficiently, about 80% efficiency. If we used TALENs, a more recent and complicated development in genetic engineering, we got 30% efficiency for just one gene."

Because the CRISPR/Cas technique can generate mutant mice even without using ES cells, a limitation of the conventional method for making models, genetic research may no longer be confined to a limited list of model organisms?those for which ES cells exist.

"This breaks down the definition of model organism," says Wang, a postdoctoral researcher in Jaenisch's lab. "So now, even with limited resources, any animal with established embryo manipulation procedures could be the subject of genome engineering. With many of the animals' genomes that have been sequenced, we could use this technology to establish efficient genetic manipulations in more species, to study the unique biology of each, and to learn more about evolution."

Thus, Wang, Yang, and Shivalila have used CRISPR/Cas to create mouse models only, but the team is excited broaden its application to other animals.

"We also need to see if the CRISPR/Cas system has any unexpected, undesired off-target effects, changes to the genome that we don't want," says Yang, a postdoctoral researcher in the Jaenisch lab. "So we need study this further to establish the fidelity of the system. But I think this will be the way to go."

###

"One-step generation of mice carrying mutations in multiple genes by CRISPR-Cas mediated genome engineering"

Cell, May 9, 2013

Whitehead Institute for Biomedical Research: http://www.wi.mit.edu/index.html

Thanks to Whitehead Institute for Biomedical Research for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

This press release has been viewed 29 time(s).

Source: http://www.labspaces.net/128114/Scientists_create_genetically_altered_mice_to_model_human_disease

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Friday, May 3, 2013

Don't blame Canada: Former ambassador to Iran on Argo, America, and nukes

Canada's envoy to Tehran at the time of the Islamic revolution and the US hostage crisis, says Argo disappointed him and that he's worried about where Iran's nuclear program might lead.

By Ariel Zirulnick,?Staff writer / April 26, 2013

Former Canadian Ambassador to Iran Ken Taylor and his wife Pat, pose for photographers at the premiere of the film Argo in Washington, Oct. 2012. Taylor, who protected Americans at great personal risk during the Iran hostage crisis of 1979, has achieved some name recognition in the US since the 2012 movie 'Argo' swept theaters and the Academy Awards.

Cliff Owen/AP/File

Enlarge

Former Canadian Ambassador Ken Taylor is neither the James Bond lookalike he hoped might portray him in the Hollywood blockbuster "Argo" nor is he quite the Austin Powers double he says might have been a more accurate choice.

Skip to next paragraph Ariel Zirulnick

Middle East Editor

Ariel Zirulnick is the Monitor's Middle East editor, overseeing regional coverage both for CSMonitor.com and the weekly magazine. She is also a contributor to the international desk's terrorism and security blog.?

Iran then

When Taylor arrived in Tehran in 1977, ?the country was booming.?

There were rumors that Mohammed Reza Shah Pahlavi ? more commonly referred to as simply ?the Shah? ? was preparing to buy Pan American Airways. It did not seem like the ?stalwart of the West? was going anywhere.

For all the blame heaped on the Central Intelligence Agency (CIA) for not predicting the Islamic Revolution, almost nobody saw it coming, he said. Afterward, the Ayatollah?s secular advisers told Taylor that even they didn?t expect the Shah?s government to fall like it did. ?

Revolutionary fervor did not sweep up the whole country the way it seemed to be portrayed in "Argo." And Taylor said a great disappointment for him was the way the movie portrayed Iranians, some of whom became ?marvelous friends? with him during his posting in Tehran.

?The movie was too heavy handed,? he said. ?It gave no idea that there is another side to the Iranian character. Everybody isn?t on the street. Everybody isn?t part of the revolution.?

Too many sanctions, too little talking

He is on board with the growing chorus of voices in Washington urging the Obama administration to ease up on its sanctions-heavy approach to negotiations with Iran although he acknowledges that Iran needs to give ground too.

Sometimes sanctions work, he says, citing South Africa during the apartheid era, but ?sometimes they strengthen resolve.?

When asked his opinion of whether Tehran has nuclear weapon ambitions, he cautions that ?Iran is an opaque society,? and there?s too little information to guess.

?I think they?ve got some military use in the back of their mind,? he says. ?But they don?t want to destroy themselves ? Maybe they are working at capabilities, but not necessarily producing [a nuclear weapon].?

That the military option for halting Iran?s nuclear development is ?on the table? worries Taylor, who points to the wars in Iraq and Afghanistan as cautionary for anyone considering going to war with Iran.

"A bombing mission would be a fatal error. It would solve nothing,? he says. ?It would postpone [Iran?s nuclear program] for two to three years,? but nothing more, because Iran?s nuclear facilities are too dispersed.

He says, ?I wake up every morning hoping [the military option] is still on the table? ? instead of being used.

Source: http://rss.csmonitor.com/~r/csmonitor/globalnews/~3/hjWdZ6cfd7U/Don-t-blame-Canada-Former-ambassador-to-Iran-on-Argo-America-and-nukes

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Twitter hires Morgan Stanley banker with IPO, M&A background

May 1 (Reuters) - Post position for Saturday's 139th Kentucky Derby at Churchill Downs after Wednesday's draw (listed as barrier, HORSE, jockey, trainer) 1. BLACK ONYX, Joe Bravo, Kelly Breen 2. OXBOW, Gary Stevens, D. Wayne Lukas 3. REVOLUTIONARY, Calvin Borel, Todd Pletcher 4. GOLDEN SOUL, Robby Albarado, Dallas Stewart 5. NORMANDY INVASION, Javier Castellano, Chad Brown 6. MYLUTE, Rosie Napravnik, Tom Amoss 7. GIANT FINISH, Jose Espinoza, Tony Dutrow 8. GOLDENCENTS, Kevin Krigger, Doug O'Neill 9. OVERANALYZE, Rafael Bejarano, Todd Pletcher 10. PALACE MALICE, Mike Smith, Todd Pletcher 11. ...

Source: http://news.yahoo.com/twitter-hires-morgan-stanley-banker-ipo-m-background-174739753.html

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